Alpha Ketoglutarate
【CAS No.】: 328-50-7
【Molecular Formula】: C5H6O5
【Active ingredients】: Alpha-Ketoglutarate
【Specification】: Alpha-Ketoglutarate 99%
【Appearance】: White to yellowish powder
Alpha Ketoglutarate Product Details Page
α-Ketoglutaric acid is one of the two keto derivatives of glutaric acid, white fine crystalline powder. α-Ketoglutaric acid participates in the tricarboxylic acid cycle in organisms, produces amino acids, and can be used as a dietary supplement. α-Ketoglutaric acid is an important metabolic intermediate in the tricarboxylic acid cycle of microorganisms and a key node connecting carbon-nitrogen metabolism in cells. Its position in the cycle is after isocitrate and before succinyl-CoA. At this site, the anaplerotic reaction can achieve the purpose of replenishing this intermediate metabolite by producing α-ketoglutaric acid through the transamination of glutamate, and this purpose can also be achieved by glutamate dehydrogenase acting on glutamate. Glutamate can generate glutamine under the action of glutamine synthase, which uses one molecule of ATP to produce glutamyl phosphate; this intermediate is attacked by ammonia as a nucleophile to form glutamine and inorganic phosphate.
Shaanxi Rebecca Biotechnology Co., Ltd. focuses on providing high-qualityAlpha-Ketoglutarate Powder to large purchasers to meet your large-scale, high-standard purchasing needs. The α-ketoglutarate powder we provide is a high-quality health supplement made from α-ketoglutaric acid. α-Ketoglutarate is an important component of the tricarboxylic acid cycle, which is a key process for cells to produce energy. α-Ketoglutarate powder is a white or slightly yellow crystalline or crystalline powder. Welcome to Shaanxi Rebecca Bio-Tech Co., LTD! We take pride in delivering high-quality, pure, and natural plant-based products like Alpha Ketoglutarate, designed to meet the diverse needs of industries worldwide. Explore how this essential compound can benefit your business.
1. Why choose us?
Source manufacturer, quality assurance: Shaanxi Rebecca Bio-Tech Co., Ltd. has advanced production equipment and a strict quality control system to ensure that each batch of α-ketoglutarate meets the standards.
Adequate production capacity and stable supply: We have a large production base with an annual output of up to 10 tons, which can meet your large-scale purchasing needs and ensure stable supply.
Price advantage, win-win cooperation: As a source manufacturer, we save the middle link and provide you with more competitive prices to achieve win-win cooperation.
Professional team, thoughtful service: We have an experienced sales and technical team to provide you with all-round support from product consultation to after-sales service.
If you have any questions about our products, please contact us at information@sxrebecca.com.
2. Specifications
Alpha-Ketoglutarate Powder is the abbreviation of α-ketoglutarate, also known as glutaric acid. It is an important metabolite in the tricarboxylic acid cycle (i.e., citric acid cycle) and plays a variety of important roles in cells.
| Specification | Details |
|---|---|
| Appearance | White crystalline powder |
| Purity | ≥ 98% |
| Solubility | Soluble in water |
| pH (1% Solution) | 3.0 - 4.0 |
| Loss on Drying | ≤ 0.5% |
| Heavy Metals | ≤ 10 ppm |
| Arsenic | ≤ 1 ppm |
| Lead | ≤ 3 ppm |
| Assay (by HPLC) | 99.0% - 101.0% |
| Microbial Limits | < 1000 CFU/g |
| Yeast & Mold | < 100 CFU/g |
| Escherichia coli | Negative |
| Salmonella | Negative |
3. Benefits of Alpha-Ketoglutarate Powder
1. Enhanced Energy Production:
- ATP Synthesis: AKG powder is crucial for the production of ATP, the primary energy currency of the cell, by facilitating the Krebs cycle.
2. Antioxidant Properties:
- Cell Protection: Akg alpha ketoglutarate can help neutralize free radicals, reducing oxidative stress and potentially protecting cells from damage.
3. Muscle Growth and Recovery:
- Protein Synthesis: Alpha ketoglutaric acid can enhance protein synthesis, which is beneficial for muscle growth and repair. This is particularly useful for athletes and those involved in intense physical training.
- Reduced Muscle Fatigue: By improving energy efficiency at the cellular level, Akg alpha ketoglutarate might help reduce muscle fatigue during prolonged physical activities.
4. Kidney Health:
- Ammonia Detoxification: Alpha ketoglutarate powder plays a role in detoxifying ammonia in the kidneys, which can be beneficial for kidney function and overall renal health.
5. Collagen Formation:
- Skin Health: 2-OXOGLUTARIC ACID can assist in the production of proline, an amino acid essential for collagen synthesis, which is vital for skin, bone, and connective tissue health.
6. Immune System Support:
- Glutamine Production: AKG can be converted into glutamine, which is important for immune function, gut health, and muscle recovery.
7. Neuroprotection:
- Brain Health: There is some research suggesting that AKG might have neuroprotective effects, potentially aiding in the prevention of neurodegenerative diseases by supporting energy metabolism in brain cells.
8. Anti-Aging:
- Cellular Health: By enhancing mitochondrial function and reducing oxidative stress, AKG might contribute to slower aging at the cellular level.
9. Cardiovascular Health:
- Blood Pressure Regulation: Some studies indicate that Alpha-Ketoglutarate Powder might help in regulating blood pressure, although more research is needed in this area.
10. Metabolic Health:
- Weight Management: Preliminary studies suggest that AKG might influence metabolic pathways in a way that could support weight management efforts, though this area requires further exploration.
4. Application Areas of Alpha-Ketoglutarate Powder
Medical field:Alpha-Ketoglutarate Powder is an intermediate metabolite of the tricarboxylic acid cycle in organisms, and participates in the synthesis and energy metabolism of amino acids, vitamins and organic acids. It plays an important role in reducing the body loss of postoperative patients and long-term patients. In addition, α-ketoglutaric acid also has multiple physiological activities such as antioxidant and anti-inflammatory, can neutralize free radicals, and plays a key role in maintaining the health of organisms. α-ketoglutaric acid can also be used as a raw material for drugs to make antioxidants, immunomodulators and anti-inflammatory drugs, etc., which have a positive impact on the treatment and prevention of diseases.
Agricultural field: It can act as a coenzyme of amino acid transaminase, participate in the metabolism and transport process of amino acids, thereby enhancing the absorption and utilization efficiency of nitrogen sources in the soil by plants. This can not only provide the nitrogen elements needed for plant growth, but also accelerate the growth rate of plants and increase yields. In addition, α-ketoglutaric acid can also affect the absorption of phosphorus and potassium elements. By regulating the growth and development of plant roots, α-ketoglutaric acid can enhance the plant's ability to absorb phosphorus and potassium elements in the soil, improve the growth of plants and enhance their yield stability.
Food industry: It can be used as an ingredient in sports nutrition drinks to provide athletes with energy and supplement necessary nutrients. At the same time, α-ketoglutaric acid can also be used as an organic intermediate, biochemical reagent, and supporting reagent for measuring liver function, providing an important tool for biochemical research and medical diagnosis.
Animal nutrition field:It can be used as a nutritional supplement to improve the growth performance and health of animals. Studies have shown that adding an appropriate amount of α-ketoglutaric acid to feed can promote protein synthesis, improve meat quality, and enhance immune system function, thereby improving the overall health of animals. In addition, α-ketoglutaric acid can also participate in the energy metabolism process, improve energy supply efficiency, reduce stress response, and help animals restore physiological balance faster.
5. Packaging and Transportation
Packaging:
- Standard packaging: 1kg, 5kg, or 25kg sealed bags.
- Customizable packaging options available upon request.
Transportation:
- Reliable global shipping partners.
- Guaranteed timely delivery with robust tracking systems.
6. Qualification Certification
Our Alpha Ketoglutarate meets global quality and safety standards:
- ISO 9001 Certified
- GMP Compliant
- FDA Registered Facility
- Third-party testing reports available
7. FAQs
Q1: Is your Alpha Ketoglutarate suitable for vegans?
Yes, our product is 100% plant-based and vegan-friendly.
Q2: Can I request custom formulations?
Absolutely! We provide tailored solutions to meet your specific needs.
Q3: What is the typical lead time for bulk orders?
Standard orders ship within 5–7 business days. Larger orders may require additional time.
Q4: How do you ensure product stability during shipping?
Our packaging is designed to preserve the integrity and stability of the product throughout transit.
8. Contact Us
Boost Your Business with High-Quality Alpha Ketoglutarate Today! By choosing Shaanxi Rebecca Bio-Tech, you gain a reliable supplier committed to delivering excellence, optimizing your supply chain, and meeting your production needs efficiently. For inquiries, sample requests, or placing an order, email us at information@sxrebecca.com. Let Shaanxi Rebecca Bio-Tech Co., LTD be your trusted partner for premium Alpha Ketoglutarate and more.
