Nonivamide <br>Synthetic Capsaicin<br>

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Synthetic Capsaicin Powder Introduction

Synthetic Capsaicin Powder also named Nonivamide is also called pelargonic acid vanillylamide or PAVA. It is a capsaicinoid. Nonivamide, isolated from peppers, is a naturally occurring analog of capsaicin (sc-3577). Similar to capsaicin, nonivamide can activate the TRPV1 receptor, thus, stimulate the firing rate of dopaminergic neurons in the ventral tegmental area of the brain and to increase the expression of the serotonin receptor gene HTR2A. Nonivamide is with lower TRPV1 binding affinity, thus, a reduced pungency (9 200 000 scoville heat units)

compared to capsaicin (16 000 000 scoville heat units).

In Chinese words, Synthetic Capsaicin Nonivamide, is the same word, to be exact,Synthetic Capsaicin means the same product: Nonivamide. So, Synthetic Capsaicin Nonivamide is one product, comparing with the Natural Capsaicin,which is different and which is extracted from Natural Chilli and have sky-up high price.Nonivamide has a chemical structure which is similar to natural capsaicin compounds and has similar biological activities as natural Capsaicin. But Nonivamide has absolute advantages over natural capsaicin in terms of price and spiciness, so it has a much broader Application fields.

Shaanxi Rebecca Bio-Tech Co., Ltd., where we are dedicated to delivering high-quality and innovative plant-based products that support human health. Our Synthetic Capsaicin Powder offers a pure, stable, and effective alternative to natural capsaicin, ideal for applications in pharmaceuticals, biotechnology, and health industries. Formulated using advanced ultra-fine grinding and high-temperature drying processes, it maintains consistent potency and purity, meeting the highest standards of efficacy.

We look forward to hearing from you and establishing cooperation with you. If you have any questions about our products, you can contact us by information@sxrebecca.com at any time. We are happy to answer all your questions.

COA Analysis Report

We provide a detailed Certificate of Analysis (COA) to ensure all batches meet stringent purity, stability, and regulatory requirements. The COA includes testing

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Qualification Certification

HPLC Chromatogram

SGS Test Report on Purity of Nonivamide

SGS Test Report of Nonivamide

SGS Lab, conducted a Full Analysis of Nonivamide (Synthetic Capsaicin),And Test Report says: All Test Results are conforming with Both Chinese Pharmacopoeia and Japanese Pharmacopoeia.

So,Our Nonivamide (Synthetic Capsaicin), is totally Qualified to be used in External-use Pharmaceutical Products.

Specifications of Nonivamide

Product Name:	Nonivamide
Synonyms:	Nonivamide(Synthetic Capsaicin);N-((Hydroxy-3-methoxyphenyl)methyl)4-nonanamide;N-Nonanoyl vanillylamide;Nonanamide, N-((4-hydroxy-3-methoxyphenyl)meth;SYNTHETIC CAPSAICIN;PELARGONYL VANILLYLAMIDE;PELARGONIC ACID VANILLYLAMIDE;N-PELARGONIC ACID VANILLYLAMIDE
CAS:	2444-46-4
MF:	C17H27NO3
MW:	293.4
EINECS:	219-484-1
Product Categories:	Anilines, Aromatic Amines and Nitro Compounds;INORGANIC & ORGANIC CHEMICALS;Plant extract;Herb extract;Inhibitors;API;2444-46-4

Scoville Heat Unit or Scoville Hotness Units

Scoville designed a set of experimental methods called "Scoville Organoleptic test" to measure capsaicin content. This method is to dissolve one unit of capsaicin in the sugar water, and then give it to several people to taste, and then gradually increase the amount of sugar water until the spicy taste cannot be tasted. Scoville Hotness Units (SHU). For example, bell peppers have no spicy taste when eaten raw, so the SHU is 0~5; the SHU of allspice is between 100 and 500, which means that one unit of allspice requires 100~500 times of sugar water to neutralize. The substance with the highest SHU value is capsaicin, which

is around 15,000,000~16,000,000. Because this experimental method is greatly influenced by human subjectivity, later generations developed a method called "high performance liquid chromatography" (HPLC) to measure. However, because the Scoville indicator has been in use for a long time, the measurement value of high performance liquid chromatography is still often converted into SHU to represent the capsaicin content.

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The uses of synthetic capsaicin

(1) Food Industry

In Some countries, like some Asia and Europe countries, Synthetic Capsaicin（NSC 172795） is listed as an approved Food Additive. So, It has been used in Food Industry for many years.

(2) Pharmaceutical Field

It has ideal functions of pain-relieve, anti-inflammatory, clearing meridian, activating collaterals, activating blood, and removing blood stasis. It can be made into sprays, liniments, tinctures, creams, patches,fever patches, etc. Which are for addiction-free analgesia, bacteria and fungi, promote circulation, etc. It has been widely used in External-use Medicines,like synthetic capsaicin ointment,External patchs, treatment of rheumatism, bruises, frostbite, antipruritic, antiseptic,anti-inflammatory and many other medicines.

(3) Biological Pesticides

The microemulsion made by synthetic capsaicin powder is a kind of plant-derived environmentally friendly biological insecticide. It has the characteristics of high efficacy, long lasting period, good safety, and no pollution to the environment. It is an ideal non-pollution pesticide.

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(4) Anti-rat and Anti-ant repellent

N-Vanillylnonanamide has a strong and long-lasting pungent taste, a small amount of addition can prevent rodents from chewing, and it can kill Termites, ants, so it is widely used in PE or PVC protective sheaths in cables and optical cables manufacturing fields. This application has been taken by cables and optical cables Manufacturers for many years.

(5) Pollution-free biological antifouling agent

Currently, as a Biological antifouling agent, it has been used in antifouling paints and coatings on ships, offshore platforms, and underwater facilities to prevent the adhesion of algae, shellfish, mollusks and other marine organisms, it can prevent the accumulation of aquatic organisms. It can replace toxic organic-tin antifouling agent.

(6) Military and self-protection fields

Pelargonic acid Vanillylamide has a strong sneezing effect, this can be used in some military.And self-protection products, like sprayer, etc.

Applications

The powder has a range of applications across several industries:

Pharmaceuticals: Used as a potent ingredient for topical pain relief creams, patches, and gels. It is effective for conditions such as muscle and joint pain, and post-surgical pain management.

Biotechnology: Essential for research related to pain pathways and the development of new therapeutic agents.

Contract Research Organizations (CROs): Ideal for clinical trials involving pain relief and anti-inflammatory drugs.

Contract Manufacturing Organizations (CMOs): A reliable ingredient for large-scale production of pain management products.

Academic Research Institutions: Employed in studies exploring the neurobiology of pain and inflammation.

Government and Non-Profit Organizations: Used in the development of treatments for public health issues related to pain management.

Why Choose Us?

Quality Assurance: Our Nonivamide is produced under strict GMP guidelines, ensuring purity and stability.

Customization: We offer tailored solutions, adjusting concentration and formulation to meet specific client needs.

Reliable Supply: With a robust supply chain, we guarantee consistent availability for bulk orders.

Technical Support: Our team provides ongoing support and application advice to optimize your product development.

Production Process

Our Nonivamide Powder is produced through a meticulous process that includes:

Raw Material Sourcing: We use the highest quality raw plant materials, ensuring natural and pure content.

High-Temperature Drying: This process preserves essential nutrients while maintaining stability.

Ultra-Fine Grinding: This ensures the powder retains its bioactive properties and is easy to incorporate into various formulations.

Purification: We use advanced purification technologies to guarantee a high degree of purity and bioactivity.

Shipping Samples

For first-time clients or custom orders, we offer sample shipments for testing and evaluation.

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Some pictures of Nonivamide packaging

Transportation

We support shipping by air, sea, FedEx, DHL, TNT, EMS, UPS, SF, and other carrier.

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About us

Shaanxi Rebecca Bio-Tech Co.,LTD, specializes in Research&Production on plant extracts, isolation of active ingredients of traditional Chinese medicine and functional compound formulations of traditional Chinese medicine. We have a high-quality technical R&D team with strong technical force, many experienced R&D personnel, an excellent marketing team and domestic regional channel partners. We specialize in product market development and product after-sales service, and are committed to serving customers all over the world. We provide high-quality natural herbal extracts to customers in the pharmaceutical, health care products, beverages, cosmetics and other industries.

At Rebecca, we follow market development trends and actively develop innovative products on the premise of continuity and diversity of herbal medicines. We believe that natural specialty ingredients and innovative technologies are the best basis for us to meet our customers' needs. There are other related high-quality products under our main categories, and we also support customized services.
As a professional manufacturer of Chinese plant and herbal extracts, we firmly believe that natural, healthy and functional products are our unremitting pursuit of excellence.

We are looking forward to working with you!!!

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FAQ

Q: Is Synthetic Capsaicin Powder suitable for sensitive applications?

A: Yes, it is highly purified and tested to minimize side effects.

Q: Can I request a COA before purchase?

A: Absolutely, please contact us for the latest batch COA.

Q: What is the MOQ?

A: No MOQ, Customers can buy whatever the quantities that they need.

Q: Can I request a Sample before purchase?

A: Absolutely, We would like to provide Free Sample: 100grams.

Q: Can I get Technical Support from you?

A: Yes,We have experiences of 13 years on Production and 10years on Export . So, we would love to provide technical support to customers.

Q: What are the storage conditions?

A: Store in a cool, dry place away from direct sunlight.

Feel free to reach out to us at information@sxrebecca.com for more details. We look forward to serving your needs for high-quality, reliable Synthetic Capsaicin Powder.