Does gotu kola extract reduce anxiety?
Gotu kola extract, derived from the Centella asiatica plant, has gained recognition as a potential natural solution for stress and anxiety management. This herb, rich in triterpenoids and saponins, has been used in traditional medicine for centuries. Recent scientific studies suggest that gotu kola extract may help regulate cortisol levels, reduce anxiety symptoms, and promote overall mental well-being. As more people seek alternatives to conventional medications, gotu kola extract emerges as a promising option for those looking to alleviate stress and anxiety through natural means.
English name: Gotu Kola Extract
Latin Name:Centella Asiatica(L.) Urban
active ingredients: asiaticoside
Specification: 10%-90%
CAS No.: 16830-15-2
Molecular forula: C48H78O19
Molecular Weight: 959.12
Use Part : The whole herb
Appearance: Brown-yellow to White Powder
Mesh size:80 Mesh
Test Method: HPLC
Gotu Kola Impacts Cortisol Levels
Gotu Kola's Adaptive Stress Response Mechanism
Gotu kola extract exhibits adaptogenic properties, helping the body maintain balance in response to stress. The active compounds in gotu kola, particularly asiaticoside and madecassoside, interact with the hypothalamic-pituitary-adrenal (HPA) axis, which regulates cortisol production. By modulating this system, gotu kola may help normalize cortisol levels, preventing excessive secretion during stressful situations.
The extract's influence on neurotransmitters like GABA and serotonin also contributes to its stress-reducing effects. These neurotransmitters play crucial roles in mood regulation and stress response. By enhancing their activity, gotu kola extract may help create a more balanced neurochemical environment, better equipped to handle stress.
Clinical Studies on Gotu Kola and Cortisol Reduction
Several clinical studies have investigated the effects of gotu kola extract on cortisol levels and stress response. A study published in the Nepal Medical College Journal found that participants who took gotu kola extract experienced significant reductions in anxiety symptoms compared to those who received a placebo. While this study didn't directly measure cortisol levels, the reduction in anxiety symptoms suggests a potential impact on stress hormones.
Another study, published in the Journal of Clinical Psychopharmacology, examined the effects of gotu kola on acoustic startle response, a measure of anxiety. The results showed that gotu kola extract significantly reduced the startle response, indicating its potential to modulate stress reactions at a physiological level.
Optimal Dosage for Cortisol Management with Gotu Kola
Determining the optimal dosage of gotu kola extract for cortisol management can be challenging due to variations in extract potency and individual needs. However, most studies have used doses ranging from 500 to 2000 mg of standardized extract daily. It's crucial to start with a lower dose and gradually increase it while monitoring for any side effects.
The concentration of active compounds, particularly asiaticoside and madecassoside, is an important factor in determining dosage. High-quality extracts with standardized levels of these compounds may be more effective at lower doses. Always consult with a healthcare professional before starting any new supplement regimen, especially when aiming to manage stress and cortisol levels.
Gotu Kola vs. Prescription Anti-Anxiety Medications
Comparing Side Effects: Gotu Kola and Benzodiazepines
When considering gotu kola extract as an alternative to prescription anti-anxiety medications, it's essential to compare their side effect profiles. Benzodiazepines, a common class of anti-anxiety drugs, are known for potential side effects such as drowsiness, dizziness, and risk of dependency. In contrast, gotu kola extract generally has a milder side effect profile.
Most users of gotu kola extract report few adverse effects. Some individuals may experience mild gastrointestinal discomfort or headaches, particularly when starting use. Unlike benzodiazepines, gotu kola doesn't appear to cause significant cognitive impairment or carry a high risk of dependency. This makes it an attractive option for those seeking long-term anxiety management solutions.
Long-term Efficacy: Natural vs. Synthetic Anxiolytics
The long-term efficacy of gotu kola extract compared to synthetic anxiolytics is an area of ongoing research. While benzodiazepines often provide rapid relief from acute anxiety symptoms, their long-term use can lead to tolerance and decreased effectiveness. Gotu kola, on the other hand, may offer more sustainable benefits without the risk of tolerance development.
Studies suggest that the adaptogenic properties of gotu kola extract may contribute to its long-term efficacy. By supporting the body's natural stress response mechanisms, gotu kola may help individuals build resilience to stress over time. This contrasts with the approach of synthetic anxiolytics, which primarily focus on symptom suppression rather than addressing underlying imbalances.
Creating a Stress-Relief Plan with Gotu Kola
Gotu Kola Supplements: Forms and Recommended Usage
Gotu kola extract is available in various forms, each with its own advantages. Capsules and tablets offer convenience and precise dosing, making them popular choices for daily supplementation. Liquid extracts provide faster absorption and flexibility in dosing. Some individuals prefer dried herb for making teas, although this method may result in lower concentrations of active compounds.
When incorporating gotu kola into a stress-relief plan, consistency is key. Many users find taking the supplement in divided doses throughout the day more effective than a single large dose. Starting with a lower dose and gradually increasing it allows individuals to assess their tolerance and identify the optimal amount for their needs.
Lifestyle Changes to Maximize Gotu Kola's Anti-Anxiety Effects
To maximize the benefits of gotu kola extract for stress and anxiety relief, incorporating supportive lifestyle changes is crucial. Regular exercise, particularly activities like yoga or tai chi, can enhance the herb's calming effects. Mindfulness practices such as meditation or deep breathing exercises can further support stress reduction when combined with gotu kola supplementation.
Dietary modifications can also play a role in optimizing gotu kola's effects. Reducing caffeine and alcohol intake while increasing consumption of omega-3 rich foods may create a more favorable environment for stress management. Additionally, ensuring adequate sleep and maintaining a consistent sleep schedule can significantly impact the body's ability to cope with stress and anxiety.


Where to Buy Gotu Kola Extract?
Shaanxi Rebeccia Bio-Tech Co., Ltd. stands out as a premier source for high-quality gotu kola extract. Our production base is equipped with internationally leading extraction, separation, and purification equipment, and operates in strict compliance with GMP and ISO standards. From raw material procurement to finished product delivery, every step undergoes rigorous quality control to ensure the safety and efficacy of our products. We offer gotu kola extract in various concentrations and forms to meet diverse manufacturing needs. To learn more about our gotu kola extract and other botanical ingredients, contact us at information@sxrebecca.com.
References
- Jana, U., et al. (2010). A clinical study on the management of generalized anxiety disorder with Centella asiatica. Nepal Med Coll J, 12(1), 8-11.
- Bradwejn, J., et al. (2000). A double-blind, placebo-controlled study on the effects of Gotu Kola (Centella asiatica) on acoustic startle response in healthy subjects. J Clin Psychopharmacol, 20(6), 680-684.
- Wanasuntronwong, A., et al. (2012). Anxiolytic effects of standardized extract of Centella asiatica (ECa 233) after chronic immobilization stress in mice. J Ethnopharmacol, 143(2), 579-585.
- Gohil, K. J., et al. (2010). Pharmacological Review on Centella asiatica: A Potential Herbal Cure-all. Indian J Pharm Sci, 72(5), 546-556.
- Gray, N. E., et al. (2017). Centella asiatica attenuates hippocampal mitochondrial dysfunction and improves memory and executive function in β-amyloid overexpressing mice. Mol Cell Neurosci, 80, 75-83.