What Is Baicalin?
Baicalin is a valuable natural active flavonoid glycoside extracted from the roots of Scutellaria baicalensis Georgi. Processed into uniform fine raw material, baicalin powder is widely used in pharmaceutical research, nutritional supplements and cosmetic development. This guide breaks down the core traits, production standards, biological effects and procurement tips of the ingredient for industry researchers and bulk buyers.

Baicalin Powder
【English name】: Baikal skullcap Root Extract
【Latin Name】: Scutellaria Baicalensis Georgi. L.
【CAS No.】:21967-41-9
【Molecular Formula】: C21H18O11
【Molecular Weight】: 446.37
【Test Method】: HPLC
【Use Part】: Root
【Main Ingredient】:Baicalin
【Specification】: 70%~98%
【Appearance】: Light Yellow Fine Powder
【Delivery】:FedEx, DHL, Ship by air, Ship by sea.
Baicalin Powder—Origin, Composition, and Health Effects
After learning the basic definition of baicalin, we will dig deeper into the source, chemical traits and functional value of baicalin. All data below comes from standard pharmacopoeia testing and third-party laboratory verification.
Botanical Source and Extraction Profile of Baicalin Powder
The raw material of baicalin powder comes from dried roots of Scutellaria baicalensis, a perennial herb growing in China, Mongolia and northern Korea. Shaanxi Province is the core planting base for high-quality skullcap roots, which cuts transportation links and keeps raw herbs fresh for extraction.
Manufacturers adopt HPLC standardized extraction technology to separate pure finished products with adjustable purity between 70% and 98%. Different purity levels match different industrial application scenarios for this natural botanical ingredient.
This light yellow fine powder has fixed stable physical indicators. Its molecular weight is 446.37 g/mol, melting point hits about 223°C, and moisture is controlled below 5%. Advanced extraction steps remove heavy metal pollutants and pesticide residues inside crude plant roots, so baicalin meets global food and medicine safety standards.
Chemical Structure and Bioavailability of Baicalin Powder
The molecular formula of pure baicalin powder is C₂₁H₁₈O₁₁, with CAS registration number 21967-41-9. Its special glycoside structure directly changes how the human body absorbs the ingredient after oral intake.
Intestinal β-glucuronidase splits the raw material into baicalein inside the digestive tract. Baicalein penetrates cell barriers more easily, which strengthens the biological efficacy of the core active substance. Formulation designers must consider this conversion rule to set reasonable serving doses for end products.
The ingredient has limited solubility in pure water and ethanol. It dissolves quickly in weak alkaline liquid environments. This feature affects product design for oral drinks, oral supplements and skin care topical formulas made with baicalin powder.
Health-Promoting Mechanisms of Baicalin Powder
A large number of laboratory studies prove that baicalin powder exerts health benefits through multiple independent and linked biological pathways.
First, it blocks NF-κB signal channels in the human body. It lowers the secretion of inflammatory substances IL-1β and TNF-α, so it relieves mild inflammatory reactions effectively.
Second, the ingredient acts as a natural antioxidant. It clears harmful reactive oxygen species (ROS) and boosts the activity of internal antioxidant enzymes such as superoxide dismutase.
Third, it lightly regulates GABA receptors in the body. It brings mild soothing effects without side effects of synthetic sedative ingredients. This trait makes baicalin powder popular in stress relief health supplements.

Purchasing and Procurement Guide for Baicalin Powder
We have covered the basic properties and functional advantages of the botanical active ingredient above. If you work in purchasing, formulation development or factory procurement, this section shares practical standards to select qualified suppliers of baicalin.
Supplier Evaluation Criteria for Baicalin Powder
Reliable manufacturers must provide complete, valid certification documents for their botanical raw materials. Key certificates include GMP production qualification, HACCP food safety certification and ISO 22000 system files. Buyers should ask suppliers to provide recent third-party test reports and real client references for baicalin powder.
When screening suppliers, prioritize factories built near Shaanxi skullcap planting zones. Local raw material supply reduces impurity risks and stabilizes batch quality of finished botanical extracts.
Professional manufacturers maintain independent R&D laboratories. The technical team can solve formulation problems and supply full regulatory documents for cross-border sales of plant-based active ingredients.
Pricing Structure and MOQ Flexibility of Baicalin Powder
The market price of baicalin changes based on purity and order quantity. Low purity 70%-85% grades suit cosmetic and general food use. High purity 98% pharmaceutical-grade materials cost more for drug research APIs.
Our brand sets flexible minimum order quantities to meet diverse client demands. Small 1kg trial orders support lab test and pilot production. Large 25kg bulk barrels meet mass manufacturing demands for finished goods.
We support OEM and private label packaging for all botanical raw materials. Customers can choose foil bags for laboratory use or standard fiber drums for factory mass production. Global buyers need to calculate customs fees and ocean/air freight to confirm the total landed cost of bulk orders.
Logistics and Compliance Verification of Baicalin Powder Export
International export of baicalin needs complete compliance paperwork to pass global customs inspection. Our full document set includes plant quarantine certificates, origin certificates and regional import compliance letters for all shipments.
We provide multiple Incoterms for international orders, such as FOB, CIF and DDP. Clients pick logistics plans matching their warehouse and customs team capacity.
The standard delivery cycle of regular grades is 2 to 3 weeks. Custom high-purity materials need 4 to 6 weeks of production lead time. All sensitive batches use temperature-controlled sealed packaging during transportation to avoid moisture damage and component degradation.

Why Our Brand Delivers Superior Baicalin Powder for B2B Partners?
With clear purchasing standards for botanical extracts in hand, you may wonder how to pick a stable long-term supplier. Our factory based in Shaanxi Province has built a complete industrial chain to supply high-quality baicalin for global B2B clients.
Advanced Manufacturing Infrastructure for Baicalin Powder
Our Shaanxi factory runs three exclusive production lines for natural plant extracts. The annual total output exceeds 500 metric tons, which supports continuous bulk supply for expanding brand partners.
We install preparative HPLC and membrane separation purification equipment on production lines. These devices remove mixed impurities to produce 98% API-grade raw materials for pharmaceutical drug development projects.
The whole production system connects digital manufacturing management software. Engineers adjust production parameters quickly to customize specifications for special formulation demands from clients seeking tailored baicalin solutions.
Comprehensive Quality Assurance System for Baicalin Powder
Quality control covers every production step of our plant-based extracts. Staff identify raw skullcap herbs and test pesticide residues before extraction. Technicians track data during production and recheck finished products before delivery.
The internal testing laboratory holds official proficiency certification. Every batch of baicalin powder gets an independent Certificate of Analysis (CoA). The document records ingredient identity, purity test data, heavy metal screening and stability test results.
Full traceability records help cosmetic and supplement brands pass third-party audits. It meets consumer demands for transparent, clean-label natural raw materials in global markets.
Technical Support and Customization Services for Baicalin Powder
We do not only sell raw botanical materials. Our professional R&D team provides free technical matching services for all buyers who purchase baicalin powder.
For beverage manufacturers: We test solubility improvement methods and check ingredient stability under high-temperature pasteurization.
For cosmetic brands: The team guides formula design. We solve compatibility problems between active ingredients and emulsion base materials, as well as anti-corrosion matching issues.
We also organize academic literature packs about core skullcap active substances. The research materials support brand teams to write scientific marketing copy and complete health claim regulatory filings.
Proven Track Record of Baicalin Powder Across Industries
Our plant extract products have stable cooperative clients across three core industries: pharmaceutical API factories, dietary supplement brands and global cosmetic manufacturers.
We once supplied consistent high-purity materials to a European skincare brand. The brand passed ISO 16128 natural ingredient certification for its soothing facial series formulated.
We also supported a North American nutritional brand. With standardized raw materials and full supporting documents, the brand successfully finished the EFSA novel food filing process for its oral supplement line.

FAQs
What purity of baicalin powder fits dietary supplement production?
Most regular oral health supplements choose 80% to 85% standard raw materials. The single serving dosage ranges from 100mg to 500mg, set based on target health functions. This conventional purity grade of baicalin powder perfectly matches civilian health product formulation needs.
Pharmaceutical research and new drug development need high-purity 95% to 98% grades. Our technical team designs targeted formulation plans once you share your finished product positioning.
How long can we get free samples of baicalin powder?
Sample orders take 3 to 5 working days to prepare. We use DHL or FedEx to send samples to global clients. You only need to cover the express delivery fee for baicalin trial samples.
What is the shelf life of sealed baicalin powder?
Unopened raw materials can be stored for 24 months under cool, dry, shaded conditions. After opening, finish using the product within 6 months and seal the package tightly to avoid moisture absorption and ensure the activity of baicalin remains stable.
Conclusion
From botanical origin to industrial procurement, this article fully explains the definition and application value of the core skullcap extract. As a natural flavonoid raw material backed by scientific research, baicalin powder delivers reliable antioxidant, anti-inflammatory and immune-support effects for drugs, supplements, drinks and skincare products.
To get stable supply of high-quality natural botanical extracts, industry buyers need to select suppliers with complete testing systems, mature extraction technology and cross-border compliance capacity. Comparing purity standards, extraction processes and application matching details helps buyers make cost-effective purchasing decisions, and builds product competitiveness in the natural ingredient market.
Partner With Us for Premium Baicalin Powder Supply
If you plan to purchase bulk natural plant extracts for factory production, research and development or cosmetic formula testing, our team provides one-stop supporting services for all B2B customers seeking high-quality baicalin powder.
· Request free customized purity samples (70%-98%)
· Get detailed technical specification sheets and latest competitive quotations
· Book 1-on-1 formulation consultation with our internal R&D team
· Obtain full regulatory document packages for cross-border customs clearance
· Customize private label packaging and OEM production for large-batch orders
Contact our professional procurement specialists anytime via email: information@sxrebecca.com. You can also browse full product information on official website sxrebecca.com. Our team arranges stability testing and regulatory guidance to match your product development timeline. We are a vertically integrated botanical extract manufacturer focused on consistent batch quality, transparent communication and long-term stable cooperative relationships with global industrial clients.
References
1. Huang Y, Tsang SY, Yao X, Chen ZY. Biological properties of baicalein in cardiovascular system. Current Medicinal Chemistry-Immunology, Endocrine & Metabolic Agents, 2005.
2. Li-Weber M. New therapeutic aspects of flavones: the anticancer properties of Scutellaria and its main active constituents Wogonin, Baicalein and Baicalin. Cancer Treatment Reviews, 2009.
3. Gao Y, Snyder SA, Smith JN, Chen YC. Anticancer properties of baicalein: a review. Medicinal Chemistry Research, 2016.
4. Zhao T, Tang H, Xie L, Zheng Y, Ma Z, Sun Q, Li X. Scutellaria baicalensis Georgi: A review of its phytochemistry, pharmacology, toxicology and clinical applications. Journal of Ethnopharmacology, 2019.
5. Shen J, Li P, Liu S, Liu Q, Li Y, Sun Y, He C, Xiao P. Traditional uses, ten-year research progress on phytochemistry and pharmacology, and clinical studies of the genus Scutellaria. Journal of Ethnopharmacology, 2021.
6. Xiao JR, Do CW, To CH. Potential therapeutic effects of baicalein, baicalin, and wogonin in ocular disorders. Journal of Ocular Pharmacology and Therapeutics, 2014.








