What is chitosan oligosaccharide?

Chitosan oligosaccharide is a bioactive compound derived from chitin, a natural polymer found in crustacean shells. This versatile substance, available as chitosan oligosaccharide powder, has gained significant attention in various industries due to its unique properties and potential health benefits. As a low molecular weight derivative of chitosan, it offers enhanced water solubility and bioavailability, making it an attractive ingredient for pharmaceutical, nutraceutical, and cosmetic applications. Its antimicrobial, antioxidant, and immune-boosting properties have sparked interest in its use as a functional ingredient in health supplements and food preservation.

Chitosan Oligosaccharide Powder

Product Name:Chitosan oligosaccharide
Assay: 90% 95% 99%
CAS No.: 148411-57-8
Molecular Formula: C12H24N2O9
Appearance: Light yellow powder
Grade: Medicine/Food/Cosmetic/Agricultural/ Feed Grade

From Chitin to Chitosan Oligosaccharide

The Natural Source of Chitin in Crustacean Shells

The journey of chitosan oligosaccharide powder begins with chitin, a naturally occurring polysaccharide abundantly found in the exoskeletons of crustaceans such as shrimp, crabs, and lobsters. Chitin serves as a structural component, providing strength and protection to these marine organisms. This renewable resource has been utilized for centuries in various applications, but its potential remained largely untapped until recent scientific advancements.

Chemical Process to Produce Chitosan Oligosaccharide

The transformation of chitin into chitosan oligosaccharide involves a multi-step process. Initially, chitin is extracted from crustacean shells through demineralization and deproteinization. The resulting chitin then undergoes deacetylation, where acetyl groups are removed to produce chitosan. To obtain chitosan oligosaccharide, the chitosan is further broken down through enzymatic or chemical hydrolysis, reducing its molecular weight and increasing its solubility.

Molecular Structure of Chitosan Oligosaccharide

Chitosan oligosaccharide powder consists of shorter chains of D-glucosamine and N-acetyl-D-glucosamine units linked by β-(1,4) glycosidic bonds. This structure gives the compound its unique properties, including improved solubility and enhanced bioactivity compared to its parent molecule, chitosan. The molecular weight of chitosan oligosaccharide typically ranges from 3,000 to 5,000 Daltons, allowing for better absorption and utilization by the body.

Key Properties of Chitosan Oligosaccharide

Biocompatibility and Biodegradability Features

One of the most remarkable aspects of chitosan oligosaccharide powder is its biocompatibility with human tissues. This natural compound integrates seamlessly with biological systems, minimizing the risk of adverse reactions. Its biodegradability ensures that it can be broken down and eliminated from the body without accumulating or causing harm. These properties make chitosan oligosaccharide an excellent candidate for various biomedical applications, including drug delivery systems and tissue engineering scaffolds.

Antimicrobial and Antioxidant Capabilities

Chitosan oligosaccharide powder exhibits potent antimicrobial activities against a wide range of bacteria, fungi, and yeasts. Its positively charged molecules interact with negatively charged microbial cell membranes, disrupting their integrity and inhibiting growth. This natural antimicrobial property has led to its use as a preservative in the food industry and as an active ingredient in wound healing products. Additionally, chitosan oligosaccharide demonstrates strong antioxidant properties, helping to neutralize harmful free radicals and reduce oxidative stress in the body. These antioxidant capabilities contribute to its potential in promoting overall health and wellness.

Water Solubility and Low Molecular Weight Advantages

Unlike its precursor chitosan, chitosan oligosaccharide boasts excellent water solubility due to its lower molecular weight. This enhanced solubility significantly improves its bioavailability and allows for easier incorporation into various formulations. The low molecular weight also facilitates better absorption through the intestinal walls, enabling more efficient delivery of its beneficial properties to the body. These advantages make chitosan oligosaccharide powder a versatile ingredient in the development of functional foods, dietary supplements, and pharmaceutical products.

Major Applications of Chitosan Oligosaccharide

Use in Pharmaceutical and Nutraceutical Industries

In the pharmaceutical sector, chitosan oligosaccharide powder has shown promise as a drug delivery vehicle, enhancing the bioavailability and efficacy of various medications. Its ability to form nanoparticles and hydrogels makes it an ideal carrier for controlled release formulations. In the nutraceutical industry, chitosan oligosaccharide is gaining popularity as a natural immune system booster supplement. Research suggests it may help stimulate the production of immune cells and enhance the body's defense mechanisms. Additionally, studies have explored its potential as a natural weight management aid, possibly by binding to dietary fats and promoting their excretion.

Applications in Agriculture and Food Preservation

Chitosan oligosaccharide powder has found valuable applications in agriculture as a plant growth promoter and natural pesticide. It can enhance crop resistance to various environmental stresses and pathogens, potentially reducing the need for chemical pesticides. In food preservation, chitosan oligosaccharide serves as a sustainable alternative to chemical preservatives. Its antimicrobial properties help extend the shelf life of perishable foods by inhibiting the growth of spoilage microorganisms. This natural preservative aligns with the growing consumer demand for clean-label products free from synthetic additives.

Potential in Cosmetics and Wound Healing Products

The cosmetic industry has embraced chitosan oligosaccharide powder for its moisturizing, anti-aging, and skin-protective properties. Its ability to form a protective film on the skin helps retain moisture and reduce transepidermal water loss. In wound healing applications, chitosan oligosaccharide has shown promise in accelerating the healing process, particularly in diabetic patients. Its antimicrobial and biocompatible nature creates an optimal environment for tissue regeneration while protecting against infections. These diverse applications highlight the versatility and potential of chitosan oligosaccharide in improving various aspects of health and wellness.

Chitosan oligosaccharide powder represents an advancement in the field of natural bioactive compounds. Its unique properties, including biocompatibility, antimicrobial activity, and enhanced solubility, make it a valuable ingredient across multiple industries. From promoting immune health to preserving food naturally, chitosan oligosaccharide continues to demonstrate its versatility and potential. As research progresses, we can expect to see even more innovative applications of this promising compound, further solidifying its place in the realms of health, agriculture, and beyond.

China Chitosan Oligosaccharide Powder Supplier

Shaanxi Rebeccia stands at the forefront of production, offering high-quality products tailored to meet the diverse needs of our global clientele. Our state-of-the-art production facility employs cutting-edge extraction, separation, and purification technologies, ensuring the highest standards of purity and efficacy. We pride ourselves on our strict adherence to GMP and ISO standards, guaranteeing consistency and quality in every batch. Our chitosan oligosaccharide powder is available in various grades, including medicine, food, cosmetic, agricultural, and feed, with assay levels of 90%, 95%, and 99%. The light yellow powder form ensures easy incorporation into a wide range of applications. Experience the difference of premium chitosan oligosaccharide backed by rigorous quality control and unwavering commitment to excellence. To learn more about our products or discuss your specific requirements, contact us at information@sxrebecca.com.

References

1. Wang, Y., et al. (2021). "Chitosan Oligosaccharides: Synthesis, Characterization and Applications." Carbohydrate Polymers, 234, 115903.
2. Kim, S.K., & Rajapakse, N. (2005). "Enzymatic production and biological activities of chitosan oligosaccharides (COS): A review." Carbohydrate Polymers, 62(4), 357-368.
3. Zou, P., et al. (2016). "Advances in characterisation and biological activities of chitosan and chitosan oligosaccharides." Food Chemistry, 190, 1174-1181.
4. Liaqat, F., & Eltem, R. (2018). "Chitooligosaccharides and their biological activities: A comprehensive review." Carbohydrate Polymers, 184, 243-259.
5. Yin, H., et al. (2009). "Characterization of antimicrobial activities of chitosan oligosaccharides against pathogenic microorganisms." Journal of Microbiology and Biotechnology, 19(2), 201-208.
6. Muanprasat, C., & Chatsudthipong, V. (2017). "Chitosan oligosaccharide: Biological activities and potential therapeutic applications." Pharmacology & Therapeutics, 170, 80-97.