What is tetrahydrocurcumin?

tetrahydrocurcumin">Tetrahydrocurcumin, a lesser-known but powerful compound, has been gaining attention in the world of health and wellness. This remarkable substance, derived from the well-known spice turmeric, offers a range of potential benefits that are capturing the interest of researchers and health enthusiasts alike.

Wholesale Turmeric Extract Tetrahydrocurcumin 99% Powder

Tetrahydrocurcumin

【English name】: Tetrahydrocurcumin
【CAS No.】: 36062-04-1
【Molecular Formula】:C21H24O6
active ingredients】: Tetrahydrocurcumin
【Specification】: Tetrahydrocurcumin 98%
【Appearance】: white powder

 

Structure: The Building Blocks of Tetrahydrocurcumin

Tetrahydrocurcumin is a metabolite of curcumin, the primary active compound found in turmeric. Its chemical structure is closely related to curcumin but with some key differences that contribute to its unique properties. Its molecular formula is C21H24O6, indicating a complex arrangement of carbon, hydrogen, and oxygen atoms.

Unlike its parent compound curcumin, which has a vibrant yellow color, it appears as a white powder. This color difference is due to the structural changes that occur during the metabolic process. The transformation from curcumin to tetrahydrocurcumin involves the reduction of double bonds in the heptadiene chain, resulting in a more stable molecule.

The structural characteristics of tetrahydrocurcumin contribute to its enhanced stability and bioavailability compared to curcumin. This stability is particularly important when considering its potential applications in various health and wellness products.

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Enhanced Bioavailability: Improving Absorption and Efficacy

One of the most significant advantages is its enhanced bioavailability compared to standard curcumin. Bioavailability refers to the extent and rate at which a substance is absorbed into the bloodstream and becomes available at the site of action. This property is crucial for the effectiveness of any compound intended for therapeutic use.

Research has shown that tetrahydrocurcumin demonstrates superior absorption and utilization by the body compared to regular curcumin. A study published in the Journal of Agricultural and Food Chemistry found that tetrahydrocurcumin had a significantly higher absorption rate and longer retention time in the bloodstream than curcumin.

The enhanced bioavailability of tetrahydrocurcumin can be attributed to several factors:

  • Improved solubility: It is more water-soluble than curcumin, allowing for better dissolution in the gastrointestinal tract.
  • Increased stability: The reduced structure makes it more resistant to degradation in the digestive system.
  • Enhanced cellular uptake: Studies suggest that tetrahydrocurcumin may have better penetration into cells, potentially leading to greater biological effects.

These factors contribute to the potential for tetrahydrocurcumin to deliver more significant health benefits at lower doses compared to standard curcumin supplements.

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Antioxidant Activity: Combating Oxidative Stress

Perhaps the most impressive characteristic is its potent antioxidant activity. Antioxidants play a crucial role in protecting our cells from damage caused by free radicals and oxidative stress. This protection is essential for maintaining overall health and potentially reducing the risk of various chronic diseases.

Tetrahydrocurcumin has demonstrated remarkable antioxidant properties in numerous studies. A comprehensive review published in the journal Molecules highlighted its superior antioxidant capacity compared to curcumin and other curcuminoids. The review noted that tetrahydrocurcumin exhibited stronger free radical scavenging abilities and more effective protection against lipid peroxidation.

The antioxidant activity contributes to its potential health benefits, including:

  • Anti-inflammatory effects: By neutralizing free radicals, tetrahydrocurcumin may help reduce inflammation throughout the body.
  • Neuroprotection: Studies suggest that tetrahydrocurcumin's antioxidant properties may help protect brain cells from oxidative damage.
  • Cardiovascular support: The compound's ability to combat oxidative stress may contribute to improved heart health.
  • Skin health: Its antioxidant activity may help protect skin cells from damage caused by UV radiation and environmental pollutants.

These potential benefits underscore the growing interest in tetrahydrocurcumin as a powerful antioxidant supplement for overall health and wellness.

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FAQ

Q1: How does tetrahydrocurcumin differ from regular curcumin?

A: Tetrahydrocurcumin is a metabolite of curcumin with a slightly different chemical structure. It offers enhanced bioavailability, improved stability, and potentially greater antioxidant activity compared to standard curcumin. Unlike the yellow-colored curcumin, tetrahydrocurcumin appears as a white powder.

Q2: What are the potential health benefits of tetrahydrocurcumin?

A: Tetrahydrocurcumin shows promise in various areas of health, including anti-inflammatory effects, neuroprotection, cardiovascular support, and skin health. Its potent antioxidant properties may help combat oxidative stress and reduce the risk of chronic diseases. However, more research is needed to fully understand its range of benefits.

Q3: Is tetrahydrocurcumin safe to consume?

A: While tetrahydrocurcumin is generally considered safe, it's always best to consult with a healthcare professional before starting any new supplement regimen. As with any compound, individual responses may vary, and potential interactions with medications should be considered.

Premium Product Specifications by Rebecca Bio-Tech

Our Tetrahydrocurcumin is manufactured to exceed industry standards, with every batch rigorously tested to ensure purity, potency, and consistency. Below are the detailed technical specifications:

  • CAS Number: 36062-04-1 (globally recognized chemical identifier for traceability)
  • Molecular Formula: C₂₁H₂₄O₆ (reflecting its hydrogenated curcumin derivative structure)
  • Molecular Weight: 372.41 g/mol (critical for dosage calculations in research and formulation)
  • Purity Specification: Minimum 98% Tetrahydrocurcumin (quantified via High-Performance Liquid Chromatography, HPLC)
  • Appearance: Fine, off-white to white powder (ensures easy blending in supplements and formulations)
  • Solubility: Soluble in ethanol, methanol, and lipid-based solutions; slightly soluble in water (optimized for diverse product formats, from capsules to liquids)
  • Heavy Metal Limits: Compliant with global standards (lead <0.1 ppm, arsenic <0.05 ppm, mercury <0.01 ppm) to guarantee safety.

Production & Quality Assurance

At Rebecca Bio-Tech, we adhere to Good Manufacturing Practices (GMP) throughout the production process to ensure uncompromised quality:

  • Raw materials are sourced from certified suppliers and undergo strict identity and purity testing before use.
  • The manufacturing process uses advanced extraction and purification technologies (e.g., column chromatography, crystallization) to isolate high-purity THC.
  • Every batch is tested by third-party laboratories for potency, contaminants, and stability, with a Certificate of Analysis (CoA) provided for full transparency.
  • Our product is non-GMO, gluten-free, and free from artificial colors, flavors, or preservatives—aligning with clean label trends in the health industry.

Versatile Applications for Diverse Needs

Whether you're advancing scientific research, developing next-gen supplements, or seeking personal antioxidant support, our Tetrahydrocurcumin delivers:

  • For Researchers: Ideal for studies on oxidative stress, inflammation, metabolic health, and neurodegenerative conditions, thanks to its high purity and predictable bioactivity.
  • For Supplement Manufacturers: Compatible with a wide range of formulations, including capsules, tablets, functional beverages, and topical skincare products (its stable structure resists breakdown during processing).
  • For Health-Conscious Individuals: Supports daily antioxidant defense, helping to mitigate the impact of environmental stressors (e.g., pollution, UV exposure) and promote overall wellness.

Partner with Rebecca Bio-Tech

To explore our Tetrahydrocurcumin in detail, request a sample for testing, or discuss custom formulations (e.g., adjusted particle size, solubility enhancements) to meet your specific needs, please contact us at information@sxrebecca.com. Our team of technical experts is ready to provide tailored support, from product selection to bulk ordering. Experience the power of this advanced antioxidant and elevate the efficacy and market competitiveness of your health-focused products with Rebecca Bio-Tech.

Tetrahydrocurcumin

References

[1] Okada, K., Wangpoengtrakul, C., Tanaka, T., Toyokuni, S., Uchida, K., & Osawa, T. (2001). Curcumin and especially tetrahydrocurcumin ameliorate oxidative stress-induced renal injury in mice. Journal of Nutrition, 131(8), 2090-2095.

[2] Somparn, P., Phisalaphong, C., Nakornchai, S., Unchern, S., & Morales, N. P. (2007). Comparative antioxidant activities of curcumin and its demethoxy and hydrogenated derivatives. Biological and Pharmaceutical Bulletin, 30(1), 74-78.