What Is The Difference Between WS 3 And WS 23 Cooling Agent?

Cooling agents are essential ingredients in various consumer products, providing that refreshing sensation we often experience in oral care products, cosmetics, and beverages. Among these cooling compounds, WS-3 and WS 23 cooling agents stand out as popular choices in the industry. This comprehensive comparison will help you understand their unique characteristics and applications.

Sensory Properties

WS-3 (N-Ethyl-p-menthane-3-carboxamide) and WS-23 (2-Isopropyl-N,2,3-trimethylbutyramide) offer distinct cooling sensations despite both being synthetic cooling agents. WS-3 provides a cooling effect that closely resembles natural menthol, with a slightly sharp onset and minty undertone. In contrast, the WS 23 cooling agent delivers a cleaner, more neutral cooling sensation without the characteristic mint notes. This makes WS-23 particularly valuable in applications where a pure cooling effect is desired without additional flavor notes.

The sensory experience of WS-23 is often described as more refined and less aggressive than WS-3. While WS-3 can sometimes create a slight tingling or numbing sensation at higher concentrations, WS-23 typically maintains a smoother profile even at increased usage levels. This characteristic has made WS-23 increasingly popular in modern formulations.

Application

Both cooling agents find extensive use across various industries, but their specific applications often differ based on their unique properties. WS-3 is commonly used in oral care products, including toothpaste, mouthwash, and breath fresheners, where its menthol-like qualities complement the traditional mint flavors. It's also frequently incorporated into pharmaceutical products for its cooling and slight analgesic properties.

WS-23, with its neutral cooling profile, has gained significant popularity in beverage applications, especially in energy drinks, sports drinks, and flavored water. Its clean cooling sensation makes it particularly suitable for fruit-flavored products where a minty note would be undesirable. The food industry also utilizes WS-23 in confectionery, chewing gum, and various snack products. In cosmetics, WS-23 is preferred in skincare formulations where a pure cooling sensation is desired without any medicinal associations.

Physical Properties

The physical characteristics of these cooling agents significantly influence their handling and formulation requirements. WS-3 appears as a white crystalline powder with a melting point that falls within the range of 96-99°C. This relatively high melting point indicates that WS-3 requires specific temperature conditions during processing and storage to maintain its solid form. In terms of solubility, WS-3 exhibits moderate solubility in water, approximately around 500 ppm at 25°C. This level of solubility means that while it can be incorporated into formulations, achieving an effective concentration in aqueous products may require careful management. Additionally, WS-3 shows good solubility in various organic solvents, providing flexibility in its use across different formulation types.

On the other hand, the WS 23 cooling agent also presents itself as a white crystalline powder, but it has a notably lower melting point of 62-63°C. This lower melting point facilitates easier handling and incorporation into various formulations. WS-23 demonstrates better water solubility than WS-3, with an approximate solubility of 1000 ppm at 25°C. This enhanced solubility is particularly advantageous for manufacturers, as it often translates to improved stability in final products. Furthermore, the increased solubility allows for more straightforward manufacturing processes, making WS-23 a preferable choice for water-based formulations. Overall, these physical properties of WS-3 and WS-23 are critical in determining their applications in various products, particularly in the cosmetics and food industries.

Cooling Intensity And Persistence

One of the most significant differences between WS-3 and WS-23 lies in their cooling intensity and duration. WS-3 typically provides a moderate cooling effect that develops gradually, allowing users to experience the cooling sensation build over time. This effect can last for about 15-20 minutes, offering a pleasant cooling experience without overwhelming the senses. The intensity of WS-3 is often described as being approximately 15-20 times that of menthol on a molecular basis, making it a popular choice for products where a milder cooling sensation is preferred.

In contrast, WS-23 offers a more potent cooling effect, estimated to be around 30 times stronger than menthol. This increased potency means that the cooling sensation provided by WS-23 is more immediate, with the onset of cooling typically occurring faster than with WS-3. Users often notice the cooling effect almost instantly, enhancing the overall sensory experience. Additionally, the effects of WS-23 can persist for a longer duration, generally lasting for 20-30 minutes under optimal conditions. This higher potency means that lower concentrations of WS-23 can achieve the desired cooling effect, potentially resulting in more cost-effective formulations for manufacturers. Overall, these differences in cooling intensity and duration make WS-3 and WS-23 suitable for different applications, catering to varying consumer preferences in the market.

WS 23 Cooling Agent For Sale

When sourcing cooling agents for commercial applications, it is crucial to work with reputable manufacturers who can provide high-quality products along with proper documentation. One such manufacturer is Rebecca Bio-Tech, which specializes in the production of the WS 23 cooling agent. They not only ensure that their products meet rigorous quality standards, but they also offer comprehensive support to their clients. This support includes free samples, allowing potential customers to evaluate the product's suitability for their specific needs before making a larger commitment. Additionally, Rebecca Bio-Tech provides essential documentation, including Material Safety Data Sheets (MSDS) and Certificates of Analysis (COA), which are vital for ensuring compliance with safety regulations and for maintaining product integrity.

The quality of cooling agents can significantly impact the final product's performance, efficacy, and overall safety. Therefore, working with established manufacturers like Rebecca Bio-Tech ensures consistent product quality and reliable technical support. This relationship can be particularly beneficial in addressing any concerns or questions that may arise during the development and formulation processes. For detailed information about WS 23 cooling agent products and the accompanying documentation, interested parties are encouraged to reach out to Rebecca Bio-Tech at information@sxrebecca.com. By doing so, they can ensure they are making informed decisions when sourcing their cooling agents.

References

1. Watson, H.R., et al. (1978). New compounds with the menthol cooling effect. Journal of the Society of Cosmetic Chemists, 29(4), 185-200.

2. Leffingwell, J.C. (2020). Cooling Compounds as Flavor and Fragrance Materials - A Review. Leffingwell Reports, 4(1), 1-27.

3. International Journal of Food Science & Technology. (2019). Applications of Cooling Agents in Food Products: Current Trends and Future Perspectives, 54(5), 1453-1464.

4. European Food Safety Authority. (2018). Safety Assessment of WS-23 as a Food Additive. EFSA Journal, 16(3), 5189.

5. Handbook of Pharmaceutical Excipients, 8th Edition. (2021). Cooling Agents in Pharmaceutical Formulations, Chapter 23, 456-460.