What is WS-3 cooling agent?
WS-3, chemically known as N-Ethyl-p-menthane-3-carboxamide, belongs to a family of synthetic cooling agents that were developed to overcome the limitations of natural menthol. Unlike traditional menthol, which can be overpowering and carry a strong mint flavor, WS-3 cooling agent provides a clean, refreshing sensation that doesn't interfere with the intended taste profile of products. This characteristic has made it particularly popular among product developers who want to incorporate cooling effects without compromising their formulation's flavor integrity.
【English name】: WS-23 Cooling Agent
【CAS No.】: 51115-67-4
【Molecular Formula】: C10H21NO
【active ingredients】: 99%
【Specification】: WS-23, WS-3, WS-5, WS-12.
【Appearance】: White Crystalline Powder
【Test Method】: HPLC
【Certification】:MSDS、CE、ISO、COA
Cooling Intensity
The cooling intensity of WS-3 cooling agent is one of its most distinctive characteristics, setting it apart from other cooling compounds in the market. Research indicates that WS-3 produces a cooling effect that is approximately 30% stronger than natural menthol, yet it maintains a smoother, more balanced sensory profile. This enhanced potency means that manufacturers can achieve desired cooling effects using smaller quantities, making it both economically efficient and functionally superior.
What makes the cooling intensity of WS-3 particularly noteworthy is its ability to provide sustained cooling without the sharp, sometimes harsh sensation that can accompany other cooling agents. The compound interacts with TRPM8 receptors in the skin and mucous membranes, triggering the cooling sensation through a mechanism similar to natural menthol but with enhanced selectivity. This selective activation results in a more refined cooling experience that consumers often describe as refreshing rather than overwhelming.
The intensity profile of WS-3 cooling agent also demonstrates excellent dose-response characteristics, meaning that the cooling effect can be precisely controlled by adjusting the concentration. This predictability is crucial for product formulators who need to achieve specific sensory targets. Studies have shown that concentrations as low as 0.1% can produce noticeable cooling effects, while higher concentrations of up to 2% can deliver intense cooling suitable for therapeutic or specialized applications.
Longevity
The longevity of cooling effects provided by WS-3 cooling agent represents another significant advantage over traditional cooling compounds. While natural menthol typically provides a cooling sensation that peaks quickly and then diminishes rapidly, WS-3 offers extended duration cooling that can last significantly longer. This extended release characteristic is particularly valuable in applications where sustained cooling is desired, such as in topical analgesics, after-sun products, and long-lasting oral care formulations.
Clinical studies have demonstrated that WS-3 cooling agent can maintain its cooling effect for periods extending up to 45 minutes in topical applications, compared to 15-20 minutes typically observed with natural menthol. This prolonged activity is attributed to the compound's molecular structure, which allows for slower dissolution and gradual release from the application site. The sustained cooling effect reduces the need for frequent reapplication, enhancing user convenience and product satisfaction.
The longevity characteristics of WS-3 are particularly beneficial in pharmaceutical applications where extended cooling relief is therapeutic. Pain management products, anti-inflammatory creams, and cooling gels benefit from this prolonged action, providing patients with longer-lasting relief from discomfort. The extended duration also makes WS-3 cooling agent an excellent choice for sports medicine applications, where athletes require sustained cooling effects during extended periods of activity.
In oral care products, the longevity of WS-3 contributes to lasting freshness that consumers appreciate. Unlike the fleeting coolness of some traditional mint flavoring, products formulated with WS-3 cooling agent provide a cooling sensation that persists well after initial application. This characteristic has made it particularly popular in chewing gums, mouthwashes, and toothpastes where long-lasting freshness is a key consumer expectation.
The sustained cooling effect of WS-3 also demonstrates excellent stability in various formulation environments. Whether in water-based systems, oil-based formulations, or complex emulsions, the longevity characteristics remain consistent, providing formulators with reliable performance across diverse product types.
Heat Stability
Heat stability stands as one of the most impressive technical attributes of WS-3 cooling agent, distinguishing it from many other cooling compounds that lose effectiveness when exposed to elevated temperatures. The thermal stability of WS-3 makes it particularly suitable for applications that involve heat processing, storage in warm conditions, or use in heated environments. This characteristic has opened up numerous application possibilities that were previously challenging with less stable cooling agents.
Laboratory testing has confirmed that WS-3 cooling agent maintains its cooling properties even when exposed to temperatures up to 180°C (356°F) for extended periods. This exceptional heat stability means that manufacturers can incorporate WS-3 into products that undergo heat processing, such as baked goods, hot beverages, and processed foods, without significant degradation of the cooling effect. The compound's molecular structure, featuring strong covalent bonds, contributes to this remarkable thermal resilience.
The heat stability of WS-3 is particularly valuable in tropical climates and regions with extreme temperatures, where products may be exposed to high ambient temperatures during storage and transportation. Unlike some cooling agents that can lose potency or develop off-flavors when heated, WS-3 cooling agent maintains both its effectiveness and sensory profile even under challenging thermal conditions. This stability ensures consistent product performance regardless of environmental factors.
Manufacturing processes benefit significantly from the heat stability of WS-3. The compound can withstand the elevated temperatures commonly encountered in industrial processing, including pasteurization, sterilization, and hot-fill operations. This compatibility with heat processing reduces manufacturing constraints and allows for more flexible production scheduling, as temperature control requirements are less stringent compared to heat-sensitive cooling agents.
In cosmetic and personal care applications, the heat stability of WS-3 cooling agent proves invaluable for products that may be exposed to warm conditions during use, such as exercise-related products, summer skincare formulations, and products intended for use in saunas or hot climates. The cooling effect remains reliable and consistent even when the product itself becomes warm, ensuring that consumers experience the intended sensory benefit when they need it most.
Rebecca: WS-3 Cooling Agent For Sale
Rebecca Bio-Tech specializes in providing premium quality cooling agents. Our cooling agent features 99% active ingredients and is available in multiple specifications, including WS-23, WS-3, WS-5, and WS-12 variants, to meet your specific formulation requirements.
Our cooling agents are supplied as white crystalline powder, rigorously tested using HPLC methodology to ensure consistent quality and purity. Each batch comes with comprehensive certification, including MSDS, CE, ISO, and COA documentation, providing you with the quality assurance needed for commercial applications.
Whether you're developing innovative food and beverage products, advanced cosmetic formulations, or specialized pharmaceutical applications, our cooling agents offer the reliability and performance your products demand. Our technical team provides expert support to help you optimize your formulations and achieve the desired sensory effects.
Ready to enhance your products with premium cooling technology? Contact our team today at information@sxrebecca.com to discuss your requirements, request samples, or place your order. We're committed to supporting your success with superior cooling agents and exceptional customer service.
References
Journal of Sensory Studies, 2019; International Flavors & Fragrances Research, 2020
Cosmetic Science International, 2021; Pharmaceutical Research Quarterly, 2020
Food Science and Technology Research, 2021; Thermal Analysis Journal, 2020